中文名稱(chēng):兔抗ATG4D多克隆抗體
Background: |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. |
Applications: |
ELISA, IHC |
Name of antibody: |
ATG4D |
Immunogen: |
Fusion protein of human ATG4D |
Full name: |
autophagy related 4D, cysteine peptidase |
Synonyms: |
APG4D; AUTL4; APG4-D |
SwissProt: |
Q86TL0 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human thyroid cancer and human liver cancer |
IHC Recommend dilution: |
50-200 |