購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：兔抗ASCC1多克隆抗體
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Background: |
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ASCC1 |
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Immunogen: |
Fusion protein of human ASCC1 |
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Full name: |
activating signal cointegrator 1 complex subunit 1 |
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Synonyms： |
p50; CGI-18; ASC1p50 |
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SwissProt: |
Q8N9N2 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and human esophagus cancer |
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IHC Recommend dilution: |
25-100 |
