中文名稱(chēng): 兔抗PSMD3多克隆抗體
英文名稱(chēng): Anti-PSMD3 rabbit polyclonal antibody
別 名: S3; P58; RPN3; TSTA2
抗 原: PSMD3
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
相關(guān)類(lèi)別: 一抗
反應(yīng)種屬: Human, Mouse
標(biāo) 記 物: Unconjugate
克隆類(lèi)型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
PSMD3 |
Immunogen: |
Fusion protein of human PSMD3 |
Full name: |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 |
Synonyms: |
S3; P58; RPN3; TSTA2 |
SwissProt: |
O43242 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human liver cancer and human ovarian cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
61 kDa |
WB Positive control: |
293T, Hela and Jurkat cells |
WB Recommended dilution: |
200-1000 |