中文名稱: 兔抗POLG多克隆抗體
英文名稱: Anti-POLG rabbit polyclonal antibody
別 名: EBP50; NHERF; NHERF1; NHERF-1; NPHLOP2
相關(guān)類別: 一抗
抗 原: POLG
儲 存: 冷凍(-20℃)
宿 主: Rabbit
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
POLG |
Immunogen: |
Synthetic peptide corresponding to a region derived from 1197-1211 amino acids of human POLG |
Full name: |
DNA polymerase gamma, catalytic subunit |
Synonyms: |
PEO; MDP1; SCAE; MIRAS; POLG1; POLGA; SANDO; MTDPS4A; MTDPS4B |
SwissProt: |
P54098 |
ELISA Recommended dilution: |
5000-10000 |
IHC Positive control: |
Human liver cancer;Human gastric cancer |
IHC Recommended dilution: |
10-50 |