購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)： 兔抗PKN1多克隆抗體
英文名稱(chēng)： Anti-PKN1 rabbit polyclonal antibody
別 名： DBK; PKN; PAK1; PRK1; PAK-1; PRKCL1; PKN-ALPHA
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： PKN1
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
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Applications: |
WB |
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Name of antibody: |
PKN1 |
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Immunogen: |
Synthesized peptide derived from Internal of human PKN1/PRK1. |
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Full name: |
protein kinase N1 |
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Synonyms： |
DBK; PKN; PAK1; PRK1; PAK-1; PRKCL1; PKN-ALPHA |
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SwissProt: |
Q16512 |
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WB Predicted band size: |
104 kDa |
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WB Positive control: |
Jurkat and Huvec cells lysates |
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WB Recommended dilution: |
500-3000 |
