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021-54845833/15800441009
中文名稱： 兔抗NPC1多克隆抗體
英文名稱： Anti-NPC1 rabbit polyclonal antibody
別 名： NPC
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： NPC1
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型 ： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
NPC1 |
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Immunogen: |
Synthetic peptide of human NPC1 |
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Full name: |
Niemann-Pick disease, type C1 |
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Synonyms： |
NPC |
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SwissProt: |
O15118 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
25-100 |
