Background: |
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. |
Applications: |
WB |
Name of antibody: |
FCGR2B(Phospho-Tyr292) |
Immunogen: |
Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32. |
Full name: |
Fc fragment of IgG, low affinity IIb, receptor (CD32) |
Synonyms: |
CD32; FCG2; CD32B; FCGR2; IGFR2 |
SwissProt: |
P31994 |
WB Predicted band size: |
34 kDa |
WB Positive control: |
K562 cells lysates treated with PMA |
WB Recommended dilution: |
500-1000 |