中文名稱: 兔抗MMP11多克隆抗體
英文名稱: Anti-MMP11 rabbit polyclonal antibody
別 名: ST3, SL-3, STMY3
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: MMP11
反應(yīng)種屬: Human, Mouse
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
MMP11 |
Immunogen: |
Synthetic peptide of human MMP11 |
Full name: |
Matrix metallopeptidase 11 (stromelysin 3) |
Synonyms: |
ST3, SL-3, STMY3 |
SwissProt: |
P24347 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human lung cancer and Human renal cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
55 kDa |
WB Positive control: |
Human colon and ovarian cancer tissue |
WB Recommended dilution: |
500-2000 |