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  • 兔抗MLANA多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW19009
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:80
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中文名稱:  兔抗MLANA多克隆抗體


英文名稱:  Anti-MLANA rabbit polyclonal antibody


別      名:  MART1; MART-1


相關(guān)類別:  一抗


儲      存:  冷凍(-20℃)


宿      主:  Rabbit


抗      原:  MLANA


反應(yīng)種屬:  Human


標(biāo)  記 物:  Unconjugate


克隆類型  rabbit polyclonal


技術(shù)規(guī)格

Background:

Melan-A (also designated MART-1) is a melanocyte differentiation antigen that is specific to melanomas, melanocyte cell lines and retina. Melan-A peptide is recognized by most HLA-A2-restricted tumor-specific tumor-infiltrating lymphocytes in patients with melanoma. Antimelanoma cytotoxic T lymphocytes can be generated with a Melan-A peptide, implicating Melan-A as a potential candidate for antigen-specific immunotherapy in melanoma patients. Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.

Applications:

ELISA, IHC

Name of antibody:

MLANA

Immunogen:

Synthetic peptide of human MLANA

Full name:

melan-A

Synonyms:

MART1; MART-1

SwissProt:

Q16655

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

40-250