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  • PPM1B抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW18359
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：90
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中文名稱：PPM1B抗原（重組蛋白）

英文名稱 PPM1B Antigen (Recombinant Protein)

別      名： PP2CB; PP2CBETA; PP2C-beta; PPC2BETAX; PP2C-beta-X

儲(chǔ)      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概      述：

Fusion protein corresponding to a region derived from 288-479 amino acids of human PPM1B


技術(shù)規(guī)格：

Full name:

protein phosphatase, Mg2+/Mn2+ dependent 1B

Synonyms:

PP2CB; PP2CBETA; PP2C-beta; PPC2BETAX; PP2C-beta-X

Swissprot:

O75688

Gene Accession:

BC012002

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.