中文名稱: IKBKE 抗原(重組蛋白)
英文名稱: IKBKE Antigen (Recombinant Protein)
別 名: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; IKKE; IKKI; IKK-E; IKK-i
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概述
Fusion protein corresponding to C terminal 250 amino acids of human IKBKE |
Full name: |
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
Synonyms: |
IKKE; IKKI; IKK-E; IKK-i |
Swissprot: |
Q14164 |
Gene Accession: |
BC107812 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]). |