中文名稱(chēng):SPHK2抗原(重組蛋白)
英文名稱(chēng): SPHK2 Antigen (Recombinant Protein)
別 名: SK 2; SK-2; SPK 2; SPK-2
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類(lèi)別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human SPHK2 |
Full name: |
sphingosine kinase 2 |
Synonyms: |
SK 2; SK-2; SPK 2; SPK-2 |
Swissprot: |
Q9NRA0 |
Gene Accession: |
BC006161 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |