中文名稱: LOXL4抗原(重組蛋白)
英文名稱: LOXL4 Antigen (Recombinant Protein)
別 名: LOXC
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 492-756 amino acids of human LOXL4 |
Full name: |
lysyl oxidase-like 4 |
Synonyms: |
LOXC |
Swissprot: |
Q96JB6 |
Gene Accession: |
BC007522 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. |