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  • LIG1抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17477
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱: LIG1抗原(重組蛋白)

英文名稱: LIG1 Antigen (Recombinant Protein)

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概  述:

Fusion protein corresponding to a region derived from C terminal 250 amino acids of human LIG1


技術(shù)規(guī)格

Full name:

ligase I, DNA, ATP-dependent

Swissprot:

P18858

Gene Accession:

BC110622

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein  in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.