購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：DNTT 抗原（重組蛋白）
英文名稱： DNTT Antigen (Recombinant Protein)
別 名： DNA nucleotidylexotransferase; TDT
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 260-509 amino acids of human DNTT |
|
Full name: |
DNA nucleotidylexotransferase |
|
Synonyms: |
TDT |
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Swissprot: |
P04053 |
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Gene Accession: |
BC012920 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. |
