中文名稱:DCT 抗原(重組蛋白)
英文名稱: DCT Antigen (Recombinant Protein)
別 名: dopachrome tautomerase; TRP-2; TYRP2
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 222-472 amino acids of human DCT |
Full name: |
dopachrome tautomerase |
Synonyms: |
TRP-2; TYRP2 |
Swissprot: |
P40126 |
Gene Accession: |
BC028311 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. The human TYRP2 protein has 83% identity and 90% similarity to the mouse sequence and has all the structural characteristics of the tyrosinase protein family, including a signal peptide, 15 conserved cysteine residues, 2 copper-binding domains, and a C-terminal membrane-spanning region. Northern blot analysis showed that TYRP2 is expressed at high levels in human melanoma cells. Its expression is regulated by the microphthalmia-associated transcription factor (MITF). |