中文名稱:BNIP3抗原(重組蛋白)
英文名稱: BNIP3 Antigen (Recombinant Protein)
別 名: NIP3
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to N terminal 164 amino acids of human BNIP3 |
Full name: |
BCL2/adenovirus E1B 19kDa interacting protein 3 |
Synonyms: |
NIP3 |
Swissprot: |
Q12983 |
Gene Accession: |
BC021989 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2. |