中文名稱:BCAT1抗原(重組蛋白)
英文名稱: BCAT1 Antigen (Recombinant Protein)
別 名: BCT1; PP18; BCATC; ECA39; MECA39; PNAS121
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 3-301 amino acids of human BCAT1 |
Full name: |
branched chain amino acid transaminase 1 |
Synonyms: |
BCT1; PP18; BCATC; ECA39; MECA39; PNAS121 |
Swissprot: |
P54687 |
Gene Accession: |
BC033864 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. |