歡迎來(lái)到上海通蔚！

021-54845833/15800441009

品質(zhì)保證 · 通蔚試劑

當(dāng)前位置: 首頁(yè) > 科研產(chǎn)品 > 科研抗體 > 其他抗體 > DAND5抗原（重組蛋白）

產(chǎn)品中心

  • DAND5抗原（重組蛋白）

    規(guī)格：
    數(shù)量：

    購(gòu)買數(shù)量

    價(jià)格：￥
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16475
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：60
  • 商品詳情
  • 參考文獻(xiàn)
  • 說(shuō)明書下載
  • 商品評(píng)論0
  • 相關(guān)產(chǎn)品
中文名稱： DAND5抗原（重組蛋白）

英文名稱： DAND5 Antigen (Recombinant Protein)

別     名： SP1; CER2; COCO; CRL2; CERL2; DANTE; GREM3; CKTSF1B3

儲(chǔ)     存： 冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

DAN domain family member 5, BMP antagonist

Synonyms:

SP1; CER2; COCO; CRL2; CERL2; DANTE; GREM3; CKTSF1B3

Swissprot:

Q8N907

Gene Accession:

BC113476

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.