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  • COL9A1 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW16251
    • 應用 : 僅限于科研使用
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中文名稱: COL9A1 抗原(重組蛋白)

英文名稱: COL9A1 Antigen (Recombinant Protein)

別     名: collagen type IX alpha 1 chain; MED; EDM6; STL4; DJ149L1.1.2

儲     存: 冷凍(-20℃)

相關類別: 抗原

概      述

Fusion protein corresponding to a region derived from 24-328 amino acids of human COL9A1

技術規(guī)格

Full name:

collagen type IX alpha 1 chain

Synonyms:

MED; EDM6; STL4; DJ149L1.1.2

Swissprot:

P20849

Gene Accession:

BC015409

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.