相關(guān)類別: 抗原
概 述
Full name: |
centromere protein O |
Synonyms: |
CENP-O; MCM21R; ICEN-36 |
Swissprot: |
Q9BU64 |
Gene Accession: |
BC002870 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. |