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    • 品牌 : 通蔚生物
    • 目錄號 : TW16191
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱:兔抗CTNNA1多克隆抗體   

英文名稱: Anti-CTNNA1 rabbit polyclonal antibody

別      名: CAP102

抗      原: CTNNA1

儲      存: 冷凍(-20℃)

宿      主: Rabbit

相關(guān)類別: 一抗

反應(yīng)種屬: Human, Mouse

標  記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

Catenin alpha-1 is a protein that in humans is encoded by the CTNNA1 gene. Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components.

Applications:

ELISA, WB, IHC

Name of antibody:

CTNNA1

Immunogen:

Fusion protein of human CTNNA1

Full name:

Catenin (cadherin-associated protein), alpha 1, 102kDa

Synonyms:

CAP102

SwissProt:

P35221

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

100 kDa

WB Positive control:

A431 cells

WB Recommended dilution:

500-2000