英文名稱: BID Antigen (Recombinant Protein)
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述
Full name: |
BH3-interacting domain death agonist |
Synonyms: |
FP497 |
Swissprot: |
P55957 |
Gene Accession: |
BC022072 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. |