中文名稱:ANAPC5 抗原(重組蛋白)
英文名稱: ANAPC5 Antigen (Recombinant Protein)
別 名: anaphase promoting complex subunit 5; APC5
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to C terminal 300 amino acids of human ANAPC5 |
Full name: |
anaphase promoting complex subunit 5 |
Synonyms: |
APC5 |
Swissprot: |
Q9UJX4 |
Gene Accession: |
BC006301 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. |