中文名稱:ALDH3A1 抗原(重組蛋白)
英文名稱: ALDH3A1 Antigen (Recombinant Protein)
別 名: aldehyde dehydrogenase 3 family, member A1; ALDH3; ALDHIII
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to C terminal 300 amino acids of human ALDH3A1 |
Full name: |
aldehyde dehydrogenase 3 family, member A1 |
Synonyms: |
ALDH3; ALDHIII |
Swissprot: |
P30838 |
Gene Accession: |
BC004370 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. |