Background: |
The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. |
Applications: |
ELISA, IHC |
Name of antibody: |
KMT2D |
Immunogen: |
Synthetic peptide of human KMT2D |
Full name: |
lysine (K)-specific methyltransferase 2D |
Synonyms: |
ALR; KMS; MLL2; MLL4; AAD10; KABUK1; TNRC21; CAGL114 |
SwissProt: |
O14686 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human brain |
IHC Recommend dilution: |
50-200 |