購(gòu)物車
幫助
021-54845833/15800441009
技術(shù)規(guī)格
Background:
The krüppel-type zinc finger transcription factors comprise a conserved family of DNA binding proteins that are important in developmental regulation. The krüppel zinc finger transcription factor was initially identified in Drosophila as a segmentation gene. Krüppel-like factors that have been characterized in mammals include erythroid krüppel-like transcription factor (EKLF), lung krüppel-like transcription factor (LKLF) and gut krüppel-like transcription factor (GKLF). EKLF is expressed principally in erythroid tissues, and LKLF expression is limited to the lung. GKLF is found predominantly in gut and has been shown to be expressed during growth arrest. In a developing mouse embryo, LKLF is necessary for normal tunica media formation and blood vessel stabilization. LKLF is also sufficient to program quiescence in T cells by negatively regulating the c-Myc-dependent pathway. The gene for human LKLF maps to chromosome 19p13.11.
Applications:
ELISA, WB
Name of antibody:
KLF2
Immunogen:
Synthetic peptide of human KLF2
Full name:
Kruppel like factor 2
Synonyms:
LKLF
SwissProt:
Q9Y5W3
ELISA Recommended dilution:
5000-10000
WB Predicted band size:
37 kDa
WB Positive control:
A549 cell lysate
WB Recommended dilution:
200-1000
