中文名稱(chēng):兔抗ACVR1C多克隆抗體
Background: |
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]). |
Applications: |
ELISA, IHC |
Name of antibody: |
ACVR1C |
Immunogen: |
Fusion protein of human ACVR1C |
Full name: |
activin A receptor, type IC |
Synonyms: |
ALK7; ACVRLK7 |
SwissProt: |
Q8NER5 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human thyroid cancer |
IHC Recommend dilution: |
15-50 |