技術(shù)規(guī)格
Background:
The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD16 (potassium channel tetramerisation domain containing 16), also known as BTB/POZ domain-containing protein KCTD16, is a 428 amino acid protein that contains one BTB (POZ) domain. An auxiliary subunit of GABAB R1 and GABAB R2, KCTD16 increases agonist potency and alters the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
Applications:
ELISA, WB, IHC
Name of antibody:
KCTD16
Immunogen:
Fusion protein of human KCTD16
Full name:
potassium channel tetramerization domain containing 16
SwissProt:
Q68DU8
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human colorectal cancer and Human thyroid cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
49 kDa
WB Positive control:
Mouse brain tissue
WB Recommended dilution:
500-2000